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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Jose | 3B | Wichita Wind Surge | 22 | 04/26/2003 | Kissimmee | USA | Switch | Right | 6' 2" | 180 lbs | - |
| Salazar, Cesar | C | Corpus Christi Hooks | 30 | 03/15/1996 | Hermosillo | MEX | Left | Right | 5' 8" | 200 lbs | - |
| Salazar, Eduardo | RP | Wichita Wind Surge | 27 | 05/05/1998 | Cumana | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Sanchez, Axel | SS | Arkansas Travelers | 23 | 12/10/2002 | Santo Domingo | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Sanchez, Edgar | RP | Midland RockHounds | 25 | 08/02/2000 | Santo Domingo | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Sanchez, Edwin | LF | Corpus Christi Hooks | 21 | 08/02/2004 | Santo Domingo | DOM | Right | Right | 6' 3" | 180 lbs | - |
| Sanchez, Yehizon | RP | Wichita Wind Surge | 25 | 11/16/2000 | La Romana | DOM | Right | Right | 6' 2" | 170 lbs | - |
| Santos II, Alex | SP | Corpus Christi Hooks | 24 | 02/10/2002 | New York | USA | Right | Right | 6' 4" | 205 lbs | - |
| Sargent, Chris | C | San Antonio Missions | 25 | 07/11/2000 | Wilmer | USA | Right | Right | 5' 11" | 185 lbs | - |
| Schiavone, Jason | 1B | Corpus Christi Hooks | 23 | 03/19/2003 | Laytonsville | USA | Right | Right | 6' 3" | 205 lbs | - |
| Scott, Connor | RF | Northwest Arkansas Naturals | 26 | 10/08/1999 | Tampa | USA | Left | Left | 6' 4" | 180 lbs | - |
| Sears, Ben | RP | Northwest Arkansas Naturals | 25 | 06/15/2000 | Providence | USA | Right | Right | 6' 5" | 205 lbs | - |
| Serretti, Danny | SS | Amarillo Sod Poodles | 25 | 05/07/2000 | Berkeley Heights | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Serven, Brian | C | Midland RockHounds | 30 | 05/05/1995 | Palm Desert | USA | Right | Right | 6' 0" | 205 lbs | - |
| Serwinowski, Adam | SP | Tulsa Drillers | 21 | 06/07/2004 | Taylors | USA | Left | Left | 6' 5" | 190 lbs | - |
| Short, Avery | SP | Amarillo Sod Poodles | 25 | 03/14/2001 | Indianapolis | USA | Right | Left | 6' 1" | 205 lbs | - |
| Shuster, Jared | RP | Springfield Cardinals | 27 | 08/03/1998 | New Bedford | USA | Left | Left | 6' 3" | 220 lbs | - |
| Simpson, Josh | RP | Arkansas Travelers | 28 | 08/19/1997 | Stafford | USA | Left | Left | 6' 2" | 190 lbs | - |
| Sirota, Mike | RF | Tulsa Drillers | 22 | 06/16/2003 | New York | USA | Right | Right | 6' 2" | 175 lbs | - |
| Smith, Drew | CL | Wichita Wind Surge | 32 | 09/24/1993 | Fort Worth | USA | Right | Right | 6' 2" | 190 lbs | - |
| Snider, Jake | LF | Frisco RoughRiders | 27 | 05/19/1998 | Champaign | USA | Left | Right | 5' 10" | 190 lbs | - |
| Solak, Nick | LF | San Antonio Missions | 31 | 01/11/1995 | Woodridge | USA | Right | Right | 5' 10" | 190 lbs | - |
| Spain, Garrett | CF | Wichita Wind Surge | 25 | 09/21/2000 | Clarksville | USA | Left | Right | 5' 11" | 180 lbs | - |
| Squires, Brett | 1B | Northwest Arkansas Naturals | 26 | 02/26/2000 | Grapevine | USA | Left | Right | 6' 3" | 210 lbs | - |
| Suarez, Christian | RP | Tulsa Drillers | 25 | 11/25/2000 | Maracay | VEN | Left | Left | 5' 11" | 160 lbs | - |
| Suisbel, Luis | 1B | Arkansas Travelers | 22 | 05/23/2003 | Valencia | VEN | Switch | Right | 6' 1" | 190 lbs | - |
| Supak, Trey | SP | Frisco RoughRiders | 29 | 05/31/1996 | Bryan | USA | Right | Right | 6' 5" | 270 lbs | - |
| Swift, Drew | 3B | Midland RockHounds | 27 | 02/15/1999 | Chandler | USA | Right | Right | 6' 0" | 165 lbs | - |
