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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabol, Blake | C | Montgomery Biscuits | 28 | 01/07/1998 | Aliso Viejo | USA | Left | Right | 6' 4" | 225 lbs | - |
| Sanchez, Carlos | 3B | Chattanooga Lookouts | 21 | 01/12/2005 | Santo Domingo | DOM | Left | Right | 6' 0" | 175 lbs | - |
| Sando, Nick | SP | Chattanooga Lookouts | 24 | 05/11/2001 | Carlsbad | USA | Left | Left | 6' 2" | 185 lbs | - |
| Scalzo Jr., Frankie | RP | Knoxville Smokies | 26 | 11/25/1999 | Vista | USA | Right | Right | 6' 3" | 190 lbs | - |
| Schoenle, Garrett | RP | Birmingham Barons | 27 | 06/21/1998 | Fort Wayne | USA | Left | Left | 6' 5" | 185 lbs | - |
| Schweitzer, Tyler | SP | Birmingham Barons | 25 | 09/19/2000 | Fishers | USA | Left | Left | 6' 0" | 185 lbs | - |
| Scull, Anthony | LF | Rocket City Trash Pandas | 22 | 01/26/2004 | Havana | CUB | Left | Left | 6' 0" | 165 lbs | - |
| Seig, Hayden | RP | Rocket City Trash Pandas | 27 | 09/10/1998 | Mechanicsburg | USA | Right | Right | 6' 5" | 225 lbs | - |
| Serna, Jared | SS | Pensacola Blue Wahoos | 23 | 06/01/2002 | Guaymas | MEX | Right | Right | 5' 7" | 170 lbs | - |
| Shade, Colby | CF | Pensacola Blue Wahoos | 24 | 08/18/2001 | Windsor | USA | Right | Right | 6' 1" | 205 lbs | - |
| Smith, Aidan | CF | Montgomery Biscuits | 21 | 07/23/2004 | Lucas | USA | Right | Right | 6' 3" | 190 lbs | - |
| Snider, Collin | RP | Knoxville Smokies | 30 | 10/10/1995 | Murfreesboro | USA | Right | Right | 6' 4" | 195 lbs | - |
| Sprinkle, Jordan | SS | Birmingham Barons | 25 | 03/06/2001 | Indio | USA | Right | Right | 5' 10" | 170 lbs | - |
| Stallings, Garrett | RP | Biloxi Shuckers | 28 | 08/08/1997 | Chesapeake | USA | Right | Right | 6' 2" | 200 lbs | - |
| Staumont, Josh | CL | Chattanooga Lookouts | 32 | 12/21/1993 | La Habra | USA | Right | Right | 6' 3" | 200 lbs | - |
| Stevens, Tristan | SP | Pensacola Blue Wahoos | 28 | 12/08/1997 | Springfield | USA | Right | Right | 6' 2" | 200 lbs | - |
| Strzelecki, Peter | RP | Biloxi Shuckers | 31 | 10/24/1994 | New York | USA | Right | Right | 6' 2" | 215 lbs | - |
