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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sammons, Bryan | SP | Erie SeaWolves | 30 | 04/27/1995 | Wilmington | USA | Left | Left | 6' 4" | 235 lbs | - |
| Sanchez, Yosber | CL | Erie SeaWolves | 24 | 05/22/2001 | Unknown | DOM | Right | Right | 6' 1" | 170 lbs | - |
| Sanders, Cam | RP | Altoona Curve | 29 | 12/09/1996 | Thibodaux | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sansone, Michael | RP | Portland Sea Dogs | 26 | 11/10/1999 | Cheshire | USA | Right | Left | 5' 9" | 195 lbs | - |
| Santucci, Jonathan | SP | Binghamton Rumble Ponies | 23 | 12/28/2002 | Leominster | USA | Left | Left | 6' 2" | 205 lbs | - |
| Schlesinger, Rafe | SP | Akron RubberDucks | 23 | 01/22/2003 | Holbrook | USA | Left | Left | 6' 3" | 200 lbs | - |
| Schoff, Tyler | RP | Harrisburg Senators | 27 | 12/06/1998 | Utica | USA | Right | Right | 6' 4" | 220 lbs | - |
| Schwartz, JT | 3B | Binghamton Rumble Ponies | 26 | 12/17/1999 | Corona | USA | Left | Right | 6' 4" | 215 lbs | - |
| Sears, Andrew | SP | Erie SeaWolves | 23 | 08/30/2002 | West Warwick | USA | Left | Left | 6' 3" | 200 lbs | - |
| Selvidge, Brock | SP | Somerset Patriots | 23 | 08/28/2002 | Chandler | USA | Right | Left | 6' 3" | 205 lbs | - |
| Sena, Reidis | CL | Portland Sea Dogs | 24 | 04/07/2001 | Neyba | DOM | Right | Right | 5' 10" | 160 lbs | - |
| Serrano III, Eli | LF | Binghamton Rumble Ponies | 22 | 05/01/2003 | Fuquay-Varina | USA | Left | Left | 6' 5" | 210 lbs | - |
| Sharp, Jacob | C | New Hampshire Fisher Cats | 24 | 09/15/2001 | La Mirada | USA | Right | Right | 5' 7" | 180 lbs | - |
| Sharpe, Davis | RP | Akron RubberDucks | 26 | 01/30/2000 | Dacula | USA | Right | Right | 6' 4" | 210 lbs | - |
| Shawver, Evan | RP | Hartford Yard Goats | 26 | 09/11/1999 | Amherst | USA | Right | Left | 6' 0" | 170 lbs | - |
| Shliger, Luke | C | Richmond Flying Squirrels | 24 | 09/25/2001 | Danbury | USA | Left | Right | 5' 9" | 180 lbs | - |
| Shuman, Seth | RP | Harrisburg Senators | 28 | 12/01/1997 | Spring Lake Park | USA | Right | Right | 6' 1" | 195 lbs | - |
| Sikkema, T.J. | RP | Portland Sea Dogs | 27 | 07/25/1998 | DeWitt | USA | Left | Left | 6' 0" | 220 lbs | - |
| Silva, Eric | SP | Erie SeaWolves | 23 | 10/03/2002 | Laguna Beach | USA | Right | Right | 6' 1" | 185 lbs | - |
| Sinclair, Jack | RP | Harrisburg Senators | 26 | 05/03/1999 | Coral Springs | USA | Right | Right | 6' 4" | 170 lbs | - |
| Smith, Austin | RP | Hartford Yard Goats | 26 | 06/22/1999 | Cedar Park | USA | Right | Right | 6' 4" | 210 lbs | - |
| Smith, Cade | SP | Somerset Patriots | 23 | 04/09/2002 | Southaven | USA | Left | Right | 6' 1" | 190 lbs | - |
| Solometo, Anthony | SP | Altoona Curve | 23 | 12/02/2002 | Winslow Township | USA | Left | Left | 6' 5" | 220 lbs | - |
| Sosa, Thomas | RF | Chesapeake Baysox | 21 | 01/18/2005 | Mella | DOM | Left | Left | 6' 1" | 160 lbs | - |
| Spivey, Carter | SP | Akron RubberDucks | 26 | 10/13/1999 | Aldie | USA | Right | Right | 6' 1" | 195 lbs | - |
| Stanifer, Gage | SP | New Hampshire Fisher Cats | 22 | 11/18/2003 | Carmel | USA | Right | Right | 6' 3" | 180 lbs | - |
| Stone, Alex | C | New Hampshire Fisher Cats | 24 | 11/03/2001 | Andover | USA | Right | Right | 6' 5" | 235 lbs | - |
| Stoudt, Levi | RP | Reading Fightin Phils | 28 | 12/04/1997 | Pottstown | USA | Right | Right | 6' 1" | 195 lbs | - |
| Strong, Jackson | RF | Erie SeaWolves | 22 | 08/26/2003 | West Seneca | USA | Left | Left | 6' 1" | 185 lbs | - |
| Stuart, Tyler | SP | Harrisburg Senators | 26 | 10/08/1999 | Kankakee | USA | Right | Right | 6' 9" | 250 lbs | - |
| Stubbs, C.J. | C | New Hampshire Fisher Cats | 29 | 11/12/1996 | Del Mar | USA | Right | Right | 6' 3" | 205 lbs | - |
| Stubbs, Garrett | C | Reading Fightin Phils | 32 | 05/26/1993 | San Diego | USA | Left | Right | 5' 10" | 170 lbs | $975,000 |
| Suarez, Joander | RP | Binghamton Rumble Ponies | 26 | 02/27/2000 | Cumana | VEN | Right | Right | 6' 3" | 250 lbs | - |
| Sugastey, Adrian | C | Richmond Flying Squirrels | 23 | 10/23/2002 | Porlamar | VEN | Right | Right | 6' 1" | 210 lbs | - |
| Susana, Jarlin | SP | Harrisburg Senators | 21 | 03/23/2004 | Villa Isabela | DOM | Right | Right | 6' 6" | 235 lbs | - |
| Swan, Eriq | SP | Harrisburg Senators | 24 | 10/31/2001 | Murfreesboro | USA | Right | Right | 6' 6" | 240 lbs | - |
| Sweet, Devin | RP | Portland Sea Dogs | 29 | 09/06/1996 | Greensboro | USA | Switch | Right | 5' 11" | 185 lbs | - |
| Sykora, Travis | SP | Harrisburg Senators | 21 | 04/28/2004 | Round Rock | USA | Right | Right | 6' 6" | 220 lbs | - |
| Szykowny, Charlie | 3B | Richmond Flying Squirrels | 25 | 06/30/2000 | Colorado Springs | USA | Left | Right | 6' 4" | 225 lbs | - |
