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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Ethan | C | El Paso Chihuahuas | 19 | 06/01/2006 | Kissimmee | USA | Left | Right | 6' 0" | 185 lbs | - |
| Sanchez, Fernando | SP | El Paso Chihuahuas | 25 | 09/13/2000 | Obregón | MEX | Left | Left | 6' 0" | 200 lbs | - |
| Sanchez, Juan | RP | Sacramento River Cats | 25 | 11/12/2000 | Valencia | VEN | Left | Left | 6' 2" | 165 lbs | - |
| Sanchez, Yolmer | 2B | Salt Lake Bees | 33 | 06/29/1992 | Maracay | VEN | Switch | Right | 5' 9" | 210 lbs | - |
| Sandlin, Nick | RP | Salt Lake Bees | 29 | 01/10/1997 | Evans | USA | Right | Right | 5' 11" | 175 lbs | - |
| Sandridge, Jayvien | RP | Salt Lake Bees | 27 | 02/11/1999 | Hagerstown | USA | Left | Left | 6' 5" | 220 lbs | - |
| Santa, Alimber | RP | Sugar Land Space Cowboys | 22 | 05/03/2003 | Azua | DOM | Right | Right | 5' 10" | 225 lbs | - |
| Santos, Gregory | CL | Sacramento River Cats | 26 | 08/28/1999 | San Cristóbal | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Santos, Winston | SP | Round Rock Express | 23 | 04/15/2002 | Payita | DOM | Right | Right | 6' 0" | 160 lbs | - |
| Saucedo, Tayler | RP | Salt Lake Bees | 32 | 06/18/1993 | Honolulu | USA | Left | Left | 6' 4" | 205 lbs | - |
| Sborz, Josh | RP | Round Rock Express | 32 | 12/17/1993 | Washington | USA | Right | Right | 6' 3" | 215 lbs | - |
| Schnell, Nick | RF | El Paso Chihuahuas | 25 | 03/27/2000 | Indianapolis | USA | Left | Right | 6' 1" | 180 lbs | - |
| Sears, JP | SP | El Paso Chihuahuas | 30 | 02/19/1996 | Sumter | USA | Right | Left | 5' 11" | 180 lbs | $2,750,000 |
| Senzel, Nick | 3B | Oklahoma City Comets | 30 | 06/29/1995 | Knoxville | USA | Right | Right | 6' 1" | 215 lbs | - |
| Seymour, Carson | RP | Sacramento River Cats | 27 | 12/16/1998 | Temecula | USA | Right | Right | 6' 5" | 255 lbs | - |
| Shields, Ben | RP | Albuquerque Isotopes | 27 | 01/23/1999 | Westwood | USA | Right | Left | 6' 4" | 210 lbs | - |
| Shook, TJ | RP | Albuquerque Isotopes | 27 | 05/29/1998 | Columbia | USA | Right | Right | 6' 4" | 215 lbs | - |
| Siani, Michael | CF | Oklahoma City Comets | 26 | 07/16/1999 | Glenside | USA | Left | Left | 6' 1" | 195 lbs | - |
| Siani, Sammy | CF | Tacoma Rainiers | 25 | 12/14/2000 | Glenside | USA | Left | Left | 5' 10" | 195 lbs | - |
| Southard, Jared | RP | Salt Lake Bees | 25 | 10/04/2000 | Leander | USA | Right | Right | 6' 2" | 220 lbs | - |
| Spence, Lucas | LF | Sugar Land Space Cowboys | 23 | 01/27/2003 | Beecher | USA | Left | Left | 6' 1" | 190 lbs | - |
| Stefanic, Michael | 2B | Las Vegas Aviators | 30 | 02/24/1996 | Boise | USA | Right | Right | 5' 9" | 180 lbs | - |
| Stephan, Josh | RP | Round Rock Express | 24 | 11/01/2001 | Grand Prairie | USA | Right | Right | 6' 3" | 185 lbs | - |
| Stevens, Chad | SS | Albuquerque Isotopes | 27 | 02/03/1999 | Fox Island | USA | Right | Right | 6' 3" | 215 lbs | - |
| Strahm, Kellen | CF | Sugar Land Space Cowboys | 28 | 04/25/1997 | Eugene | USA | Right | Right | 6' 0" | 215 lbs | - |
| Strickland, Hunter | RP | Salt Lake Bees | 37 | 09/24/1988 | Thomaston | USA | Right | Right | 6' 3" | 225 lbs | - |
| Strowd, Kade | RP | Reno Aces | 28 | 09/17/1997 | Fort Worth | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sublette, Ryan | RP | Oklahoma City Comets | 27 | 10/01/1998 | Lemont | USA | Right | Right | 6' 2" | 190 lbs | - |
| Suero, Wander | RP | Las Vegas Aviators | 34 | 09/15/1991 | Sabana Larga | DOM | Right | Right | 6' 4" | 215 lbs | - |
| Sullivan, Brett | C | Albuquerque Isotopes | 32 | 02/22/1994 | Stockton | USA | Left | Right | 5' 10" | 195 lbs | $780,000 |
| Sullivan, Joseph | 1B | Sugar Land Space Cowboys | 23 | 07/01/2002 | Birmingham | USA | Left | Left | 5' 11" | 200 lbs | - |
| Sullivan, Sean | SP | Albuquerque Isotopes | 23 | 07/22/2002 | Andover | USA | Right | Left | 6' 4" | 190 lbs | - |
| Sundstrom, Jared | RF | Tacoma Rainiers | 24 | 06/21/2001 | Santa Rosa | USA | Right | Right | 6' 2" | 230 lbs | - |
| Suwinski, Jack | LF | Oklahoma City Comets | 27 | 07/29/1998 | Chicago | USA | Left | Left | 6' 2" | 205 lbs | $1,250,000 |
