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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Brien, Riley | RP | St. Louis Cardinals | 31 | 02/06/1995 | Shoreline | USA | Right | Right | 6' 4" | 180 lbs | - |
| O'Hearn, Ryan | 1B | Pittsburgh Pirates | 32 | 07/26/1993 | Frisco | USA | Left | Left | 6' 3" | 220 lbs | $14,000,000 |
| O'Hoppe, Logan | C | Los Angeles Angels | 26 | 02/09/2000 | Birmingham | USA | Right | Right | 6' 2" | 185 lbs | $2,625,000 |
| O'Neill, Tyler | LF | Baltimore Orioles | 30 | 06/22/1995 | Burnaby | CAN | Right | Right | 5' 11" | 200 lbs | $16,500,000 |
| Ober, Bailey | SP | Minnesota Twins | 30 | 07/12/1995 | Huntersville | USA | Right | Right | 6' 9" | 260 lbs | $5,200,000 |
| Ogasawara, Shinnosuke | RP | Washington Nationals | 28 | 10/08/1997 | Fujisawa | JPN | Left | Left | 5' 11" | 205 lbs | $2,000,000 |
| Ohl, Pierson | SP | Colorado Rockies | 26 | 09/10/1999 | Simi Valley | USA | Right | Right | 6' 1" | 180 lbs | - |
| Ohtani, Shohei | DH | Los Angeles Dodgers | 31 | 07/05/1994 | Iwate | JPN | Left | Right | 6' 4" | 210 lbs | $46,000,000 |
| Okamoto, Kazuma | 3B | Toronto Blue Jays | 29 | 06/30/1996 | Gojo | JPN | Right | Right | 6' 0" | 210 lbs | $8,250,000 |
| Okert, Steven | RP | Houston Astros | 34 | 07/09/1991 | Riverside | USA | Left | Left | 6' 2" | 205 lbs | $2,325,000 |
| Oliva, Jared | CF | San Francisco Giants | 30 | 11/27/1995 | Santa Clarita | USA | Right | Right | 6' 1" | 200 lbs | $780,000 |
| Olson, Matt | 1B | Atlanta Braves | 31 | 03/29/1994 | Atlanta | USA | Left | Right | 6' 5" | 225 lbs | $22,000,000 |
| Olson, Reese | SP | Detroit Tigers | 26 | 07/31/1999 | Lula | USA | Right | Right | 6' 1" | 160 lbs | $740,000 |
| Ortiz, Joey | SS | Milwaukee Brewers | 27 | 07/14/1998 | Garden Grove | USA | Right | Right | 5' 11" | 175 lbs | - |
| Outman, James | CF | Minnesota Twins | 28 | 05/14/1997 | Redwood City | USA | Left | Right | 6' 3" | 215 lbs | - |
| Oviedo, Johan | RP | Boston Red Sox | 28 | 03/02/1998 | Havana | CUB | Right | Right | 6' 5" | 210 lbs | $1,550,000 |
| Ozuna, Marcell | LF | Pittsburgh Pirates | 35 | 11/12/1990 | Santo Domingo | DOM | Right | Right | 6' 1" | 225 lbs | $10,500,000 |
